- May 25,2023
- Posted by: Savion
One of the most widely used and safe medications for all age groups is paracetamol.
However, it has a very serious side effect, which is liver damage.
This is because paracetamol is metabolized in the liver, resulting in the production of a toxic substance called NAPQI at a rate of 10%.
Normally, the body eliminates it and excretes it through the kidneys.
However, in certain cases, the level of this toxic substance increases, such as:
- Taking an overdose of paracetamol.
- Liver problems.
- Chronic alcohol use.
- Medications that stimulate liver enzymes, such as carbamazepine and phenobarbital.